Data and results for Vieira et al., Chance and contingency in B cell evolution limit the similarity of antibody responses to infection across individuals. Code for the analyses is available at https://github.com/cobeylab/v_gene_selection
In addition to an innate immune system that battles pathogens in a nonspecific fashion, higher organ...
Virus-host co-evolution has selected for generalized host defense against viruses, exemplified by in...
Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for h...
The antibody repertoire of each individual is continuously updated by the evolutionary process of B ...
Genetics is currently undergoing a ‘big-data’ revolution, where the advent of deep-sequencing has en...
Antibodies result from the competition of B cell lineages evolving under selection for improved anti...
Antibodies are proteins released into the blood and mucosa to identify and neutralize invading patho...
The analysis of molecular signatures of antigen-driven affinity selection of B cells is of immense u...
Pathogens adapt to antibody surveillance through amino acid replacements in targeted protein regions...
The genes of the major histocompatibility complex (MHC) are a key component of the adaptive immune s...
The antibody repertoire of each individual is continuously updated by the evolutionary process of B-...
Pathogens vary in their antigenic complexity. While some pathogens such as measles present a few rel...
Affinity maturation of B cells incorporates somatic hypermutations and competition among B cell muta...
Antibodies result from the competition of B cell lineages evolving under selection for improved anti...
We analyze the interactions between division, mutation and selection in a simplified evolutionary mo...
In addition to an innate immune system that battles pathogens in a nonspecific fashion, higher organ...
Virus-host co-evolution has selected for generalized host defense against viruses, exemplified by in...
Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for h...
The antibody repertoire of each individual is continuously updated by the evolutionary process of B ...
Genetics is currently undergoing a ‘big-data’ revolution, where the advent of deep-sequencing has en...
Antibodies result from the competition of B cell lineages evolving under selection for improved anti...
Antibodies are proteins released into the blood and mucosa to identify and neutralize invading patho...
The analysis of molecular signatures of antigen-driven affinity selection of B cells is of immense u...
Pathogens adapt to antibody surveillance through amino acid replacements in targeted protein regions...
The genes of the major histocompatibility complex (MHC) are a key component of the adaptive immune s...
The antibody repertoire of each individual is continuously updated by the evolutionary process of B-...
Pathogens vary in their antigenic complexity. While some pathogens such as measles present a few rel...
Affinity maturation of B cells incorporates somatic hypermutations and competition among B cell muta...
Antibodies result from the competition of B cell lineages evolving under selection for improved anti...
We analyze the interactions between division, mutation and selection in a simplified evolutionary mo...
In addition to an innate immune system that battles pathogens in a nonspecific fashion, higher organ...
Virus-host co-evolution has selected for generalized host defense against viruses, exemplified by in...
Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for h...
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